We study how the host adaptive immune response coevolves with pathogens, especially in ways relevant to vaccine design and pathogen diversity. Our work is computational, and we collaborate closely with immunologists and epidemiologists.
Spec-seq unveils transcriptional subpopulations of antibody-secreting cells following influenza vaccination in The Journal of Clinical Investigation (2018)
Repeated vaccination may protect children from influenza infection in JAMA Network Open (2018)
Estimating vaccine-driven selection in seasonal influenza in Viruses (2018)
Use of an individual-based model of pneumococcal carriage for planning a randomized trial of a vaccine in PLOS Computational Biology (2018)