We study how the host adaptive immune response coevolves with pathogens, especially in ways relevant to epidemiological and evolutionary forecasting, vaccine design, and pathogen diversity. Our work is computational, and we collaborate closely with immunologists and epidemiologists.
Now out in eLife: We show individuals' early influenza infections shape flu epidemiology and vaccine effectiveness decades later.
July 15, 2020
Modeling infectious disease dynamics in Science (2020)
Comparison of human H3N2 antibody responses elicited by egg-based, cell-based, and recombinant protein-based influenza vaccines during the 2017-2018 season in Clinical Infectious Diseases (2019)