We study how the host adaptive immune response coevolves with pathogens, especially in ways relevant to epidemiological and evolutionary forecasting, vaccine design, and pathogen diversity. Our work is computational, and we collaborate closely with immunologists and epidemiologists.
The potential beneficial effects of vaccination on the evolution of antigenically evolving pathogens in American Naturalist (accepted) (2021)
Fractionation of COVID-19 vaccine doses could extend limited supplies and reduce mortality in Nature Medicine (2021)
Lineage-specific protection and immune imprinting shape the age distributions of influenza B cases in Nature Communications (2021)