We study how the host adaptive immune response coevolves with pathogens, especially in ways relevant to epidemiological and evolutionary forecasting, vaccine design, and pathogen diversity. Our work is computational, and we collaborate closely with immunologists and epidemiologists.
Susceptible host dynamics explain pathogen resilience to perturbations in PNAS (2026)
Cross-reactive human antibody responses to H5N1 influenza virus neuraminidase are shaped by immune history in medRxiv (2025)
Immune history shapes human antibody responses to H5N1 influenza viruses in Nature Medicine (2025)
Interplay between climate, childhood mixing, and population-level susceptibility explains a sudden shift in RSV seasonality in Japan in Nature Communications (2025)