We study how the host adaptive immune response coevolves with pathogens, especially in ways relevant to epidemiological and evolutionary forecasting, vaccine design, and pathogen diversity. Our work is computational, and we collaborate closely with immunologists and epidemiologists.
We welcome new graduate student, Rita Wang to Cobey Lab this week. Welcome Rita!
Sept. 25, 2024
Lauren McGough discusses her research goals around understanding dynamical patterns of pathogen evolution at the National Institute for Theory and Mathematics in Biology, Research-in-Progress series.
Aug. 13, 2024
Measures of population immunity can predict the dominant clade of influenza A (H3N2) in the 2017-2018 season and reveal age-associated differences in susceptibility and antibody-binding specificity in Influenza and Other Respiratory Viruses (2024)
Predicting pathogen mutual invasibility and co-circulation in Science (2024)
High-throughput sequencing-based neutralization assay reveals how repeated vaccinations impact titers to recent human H1N1 influenza strains in Journal of Virology (2024)
Vaccination against rapidly evolving pathogens and the entanglements of memory in Nature Immunology (in press) (2024)